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Composition and Biosynthesis of Sterols in Some Sponges

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image of Netherlands Journal of Zoology
For more content, see Archives Néerlandaises de Zoologie (Vol 1-17) and Animal Biology (Vol 53 and onwards).

1. The capacity of synthesizing sterols was investigated in the sponges Euspongia officinalis, Axinella damicornis, Geodia miilleri and two Halichondria species. It was found that the radioactive acetate administered to the sponges was utilized for the biosynthesis of saponifiable and non-saponifiable lipids, including sterols. 2. The sterols of Geodia, Halichondria I and Eusfiongia are Δ5 unsaturated. The sterol mixture of Euspongia is very complex, cholesterol being strongly predominant. 3. The sterols of Halichondria II and Axinella are nuclear saturated, though some Δ7 sterols are present. 4. In Axinella a series of completely new sterols was found. Identification of them is in progress.

Affiliations: 1: Laboratory of Chemical Animal Physiology, State University of Utrecht 8, Padualaan, Utrecht, The Netherlands


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