Cookies Policy

This site uses cookies. By continuing to browse the site you are agreeing to our use of cookies.

I accept this policy

Find out more here

Glutamic acid decarboxylase in the rat ampullary cristae: immunocytochemical and immunoblotting studies

No metrics data to plot.
The attempt to load metrics for this article has failed.
The attempt to plot a graph for these metrics has failed.
The full text of this article is not currently available.

Brill’s MyBook program is exclusively available on BrillOnline Books and Journals. Students and scholars affiliated with an institution that has purchased a Brill E-Book on the BrillOnline platform automatically have access to the MyBook option for the title(s) acquired by the Library. Brill MyBook is a print-on-demand paperback copy which is sold at a favorably uniform low price.

Access this article

+ Tax (if applicable)
Add to Favorites
You must be logged in to use this functionality

image of Primary Sensory Neuron
For more content, see Sensory Neuron.

In order to investigate a putative neurotransmitter function of γ-aminobutyric acid (GABA) in the rat vestibule we chose to study the cellular localization and properties of glutamic acid decarboxylase (GAD), the rate-limiting enzyme for the synthesis of GABA, in the rat ampullary cristae, with respective immunocytochemical and immunoblotting techniques, using an extensively characterized rabbit anti-GAD serum. With these procedures we found a GAD-like immunopositivity in the sensory cells and in fibers of the crista ampullaris stroma. In ampullary cristae homogenates, a GAD composed of at least two subunits (53 and 67 kDa which were present also in rat brain and cerebellum homogenates) was encountered. These findings suggest that GAD present in the rat vestibule is homologous to the brain enzyme and it has the appropriate localization to synthesize GABA to be used as a neurotransmitter in the rat vestibule.


Full text loading...


Data & Media loading...

Article metrics loading...



Can't access your account?
  • Tools

  • Add to Favorites
  • Printable version
  • Email this page
  • Subscribe to ToC alert
  • Get permissions
  • Recommend to your library

    You must fill out fields marked with: *

    Librarian details
    Your details
    Why are you recommending this title?
    Select reason:
    Primary Sensory Neuron — Recommend this title to your library
  • Export citations
  • Key

  • Full access
  • Open Access
  • Partial/No accessInformation