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Benzedrine and Social Behavior in Mice

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It is reasonably obvious that large injections of benzedrine result in some dramatic physiological and behavioral changes. However, it is not at all clear that any "peculiar" form of social behavior is induced by benzedrine doses in the order of 10 mg./kg. In the present study on mice of the C (Bagg) albino strains no definite indication was found that the mice has lost the ability to avoid one another while in movement. Rather, it would seem that the physiological effects of benzedrine stimulation were intense enough to interrupt the normal activities of sniffing, mounting, exploring, grooming and the like, and hence the mice appear to avoid each other. As the mice are hyperactive in most cases during Stage 2, CHANCE'S hypothesis regarding loss of cortical integration still may be applied to the observed changes in behavior. It is our purpose here mainly to point out that all of the behavior reported by CHANCE is not necessarily the result of benzedrine injection and that the pattern of normal social interaction must be considered.

Affiliations: 1: Departments of Psychology, University of Maryland and Bucknell University

10.1163/156853951X00250
/content/journals/10.1163/156853951x00250
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/content/journals/10.1163/156853951x00250
1951-01-01
2016-12-04

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