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Morphological, Molecular and Functional Characteristics of Two Subpopulations of Somatotropes in the Aged Male Rat

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image of Netherlands Journal of Zoology
For more content, see Archives Néerlandaises de Zoologie (Vol 1-17) and Animal Biology (Vol 53 and onwards).

Cellular heterogeneity has been described for several pituitary cell types. In the present study we have demonstrated that, in the pituitary of the ageing male rat, two subpopulations of growth hormone (GH)-producing cells occur that differ in morphological, molecular and functional aspects. These results may provide a cellular basis to the understanding of changes in GH through ageing.

Affiliations: 1: Department of Cell Biology, University of Córdoba, Spain

10.1163/156854295X01022
/content/journals/10.1163/156854295x01022
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/content/journals/10.1163/156854295x01022
1994-01-01
2016-12-10

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