Cookies Policy
X

This site uses cookies. By continuing to browse the site you are agreeing to our use of cookies.

I accept this policy

Find out more here

Adult bone marrow-derived angioblasts for improvement of cardiomyocyte function after myocardial ischemia

No metrics data to plot.
The attempt to load metrics for this article has failed.
The attempt to plot a graph for these metrics has failed.
The full text of this article is not currently available.

Brill’s MyBook program is exclusively available on BrillOnline Books and Journals. Students and scholars affiliated with an institution that has purchased a Brill E-Book on the BrillOnline platform automatically have access to the MyBook option for the title(s) acquired by the Library. Brill MyBook is a print-on-demand paperback copy which is sold at a favorably uniform low price.

This Article is currently unavailable for purchase.
Add to Favorites
You must be logged in to use this functionality

Endothelial precursors with phenotypic and functional characteristics of embryonic hemangioblasts are present in human adult bone marrow, and can be used to induce infarct bed vasculogenesis and angiogenesis after experimental myocardial infarction. The neovascularization results in decreased apoptosis of hypertrophied myocytes in the peri-infarct region, long-term salvage and survival of viable myocardium, reduction in collagen deposition, and sustained improvement in cardiac function. It is likely that co-administration of angioblasts will also be needed to supply oxygen and nutrients to exogenously administered cardiomyocyte/mesenchymal stem cells in protocols to regenerate chronically damaged myocardium. Future studies will need to address the timing, relative concentrations, source and route of delivery of each of these cellular populations in animal models of acute and chronic myocardial ischemia.

10.1163/156855801760107037
/content/journals/10.1163/156855801760107037
dcterms_title,pub_keyword,dcterms_description,pub_author
10
5
Loading
Loading

Full text loading...

/content/journals/10.1163/156855801760107037
Loading

Data & Media loading...

http://brill.metastore.ingenta.com/content/journals/10.1163/156855801760107037
Loading

Article metrics loading...

/content/journals/10.1163/156855801760107037
2017-07-25

Sign-in

Can't access your account?
  • Key

  • Full access
  • Open Access
  • Partial/No accessInformation