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The Radical Cation of N,N-Diethyl-para-Phenylendiamine : a Possible Indicator of Oxidative Stress in Biological Samples

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The alkoxy and peroxy radicals formed in the degradation of hydroperoxides brought about by transition metal ions in acidic media can convert substrates with suitably low oxidation potentials, such as N,N-diethyl-para-phenylendiamine, to the corresponding radical cations. The possibility that these reactions are used in the evaluation of oxidative stress in human beings is discussed.

Affiliations: 1: I.Co.C.EA. - CNR, Area della Ricerca, Via P. Gobetti 101, I-40129 BOLOGNA, ITALY; 2: Diacron S.r.l., Divisione diagnostici, Via Zircone 8, 1-58100 GROSSETO, ITALY

10.1163/156856700X00769
/content/journals/10.1163/156856700x00769
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/content/journals/10.1163/156856700x00769
2000-01-01
2016-12-06

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