Cookies Policy
X

This site uses cookies. By continuing to browse the site you are agreeing to our use of cookies.

I accept this policy

Find out more here

Detection and Identification of Macromolecule-Derived Radicals By Epr Spin Trapping

No metrics data to plot.
The attempt to load metrics for this article has failed.
The attempt to plot a graph for these metrics has failed.
The full text of this article is not currently available.

Brill’s MyBook program is exclusively available on BrillOnline Books and Journals. Students and scholars affiliated with an institution that has purchased a Brill E-Book on the BrillOnline platform automatically have access to the MyBook option for the title(s) acquired by the Library. Brill MyBook is a print-on-demand paperback copy which is sold at a favorably uniform low price.

Access this article

+ Tax (if applicable)
Add to Favorites
You must be logged in to use this functionality

image of Research on Chemical Intermediates

EPR spectroscopy in conjunction with spin trapping has been employed extensively and successfully to detect and identify low-molecular-weight reactive radicals in biological systems. In contrast, this technique has been relatively infrequently used to investigate high-molecular-weight species generated as a result of radical-induced damage to biological macromolecules, such as DNA, RNA, proteins and carbohydrates, despite the fact that the destruction or alteration of these materials is known to play a key role in a large number of cellular injuries and diseases. Recent progress in the detection and identification of these macromolecular radicals by EPR spin trapping is reviewed, with particular emphasis on supplementary techniques which often yield valuable information as to the nature and identity of the species detected.

Affiliations: 1: Department of Chemistry, University of York, York, YO1 5DD, U.K

10.1163/156856793X00307
/content/journals/10.1163/156856793x00307
dcterms_title,pub_keyword,dcterms_description,pub_author
6
3
Loading
Loading

Full text loading...

/content/journals/10.1163/156856793x00307
Loading

Data & Media loading...

http://brill.metastore.ingenta.com/content/journals/10.1163/156856793x00307
Loading

Article metrics loading...

/content/journals/10.1163/156856793x00307
1993-01-01
2016-12-05

Sign-in

Can't access your account?
  • Tools

  • Add to Favorites
  • Printable version
  • Email this page
  • Subscribe to ToC alert
  • Get permissions
  • Recommend to your library

    You must fill out fields marked with: *

    Librarian details
    Your details
    Why are you recommending this title?
    Select reason:
     
    Research on Chemical Intermediates — Recommend this title to your library
  • Export citations
  • Key

  • Full access
  • Open Access
  • Partial/No accessInformation