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Manipulation of Free Radical Relaxivity for Pedri

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In free radical containing solutions Proton Electron Double Resonance Imaging (PEDRI) can be used to realize useful imaging applications at a low magnetic field strength. Because of toxicity reasons the allowed radical concentration will always be limited in the case of in vivo applications. This means that the relaxivity of the radicals should be as large as possible. The parameters that determine relaxivity are discussed. It is shown that it is difficult to obtain a considerable increase in relaxivity. Some gain in relaxivity can be realized by using sizeable radicals with strongly off-centred electron spins.

Affiliations: 1: Faculty of Applied Physics, Delft University of Technology, P.O. Box 5046, 2600 GA Delft, The Netherlands

10.1163/156856796X00197
/content/journals/10.1163/156856796x00197
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/content/journals/10.1163/156856796x00197
2017-10-22

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