Cookies Policy

This site uses cookies. By continuing to browse the site you are agreeing to our use of cookies.

I accept this policy

Find out more here

Imaging of Nitric Oxide Generation in the Rat Brain

No metrics data to plot.
The attempt to load metrics for this article has failed.
The attempt to plot a graph for these metrics has failed.
The full text of this article is not currently available.

Brill’s MyBook program is exclusively available on BrillOnline Books and Journals. Students and scholars affiliated with an institution that has purchased a Brill E-Book on the BrillOnline platform automatically have access to the MyBook option for the title(s) acquired by the Library. Brill MyBook is a print-on-demand paperback copy which is sold at a favorably uniform low price.

This Article is currently unavailable for purchase.
Add to Favorites
You must be logged in to use this functionality

Cover image Placeholder

Nitric oxide radicals produced in the rat brain subjected to ischemia-hypoxia were trapped by the systemically administered diethyldithiocarbamate and iron. The right hemisphere of the brain was then removed and frozen with liquid nitrogen. Three-dimensional spatial distribution of the nitric oxide radicals in this hemisphere was performed using electron paramagnetic resonance imaging techniques. The results suggest that nitric oxide radicals were produced and trapped in the areas which are known to have high nitric oxide synthase activity, such as piriform cortex, hippocampus, hypothalamus, amygdala, and substantia nigra. In this model, which did not interrupt the posterior circulation, the production and trapping of nitric oxide in the cerebellum was relatively weak.

Affiliations: 1: Molecular and Cellular Biophysics Laboratories, Department of Medicine, Division of Cardiology & the EPR Center, Johns Hopkins Medical Institutions, Baltimore, MD 21224, USA; 2: Philadelphia Biomedical Research Institute, King of Prussia, PA 19406, USA; 3: Department of Biochemistry and Biophysics, University of Pennsylvania School of Medicine, Philadelphia, PA 19406, USA


Full text loading...


Data & Media loading...

Article metrics loading...



Can't access your account?
  • Key

  • Full access
  • Open Access
  • Partial/No accessInformation