Cookies Policy

This site uses cookies. By continuing to browse the site you are agreeing to our use of cookies.

I accept this policy

Find out more here

The association of serotonin with the spermatheca of the locust, Locusta migratoria

No metrics data to plot.
The attempt to load metrics for this article has failed.
The attempt to plot a graph for these metrics has failed.
The full text of this article is not currently available.

Brill’s MyBook program is exclusively available on BrillOnline Books and Journals. Students and scholars affiliated with an institution that has purchased a Brill E-Book on the BrillOnline platform automatically have access to the MyBook option for the title(s) acquired by the Library. Brill MyBook is a print-on-demand paperback copy which is sold at a favorably uniform low price.

This Article is currently unavailable for purchase.
Add to Favorites
You must be logged in to use this functionality

Cover image Placeholder

The association of serotonin with the spermatheca of Locusta migratoria was determined using immunohistochemistry and high performance liquid chromatography coupled to electrochemical detection. Faintly stained immunoreactive processes were seen on the spermathecal muscle but were absent in the nerves innervating the spermatheca. Immunostaining on the spermathecal muscle was enhanced using the serotonin neurotoxin, 5,7-dihydroxytryptamine, and revealed serotonin-like immunoreactive processes over the entire spermatheca. Serotonin stimulated a dose-dependent increase in the frequency of phasic contractions and the amplitude of neurally-evoked contractions of the spermatheca. Serotonin also increased the cyclic adenosine 3′,5′-monophosphate (cyclic AMP) content in all regions of the spermatheca, in the presence of the phosphodiesterase inhibitor IBMX. Octopamine had similar effects. Spermathecal tissues simultaneously exposed to octopamine and serotonin did not demonstrate cyclic AMP levels significantly different from those noted for octopamine alone. Serotonin antagonists failed to inhibit the effects of serotonin on cyclic AMP levels, with the exception of mianserin which produced inconsistent effects. Phentolamine, which totally blocks octopamine stimulated increases in cyclic AMP, reduced serotonin-stimulated cyclic AMP increases by 54% to 100%. The results suggest that serotonergic actions may, in part, be mediated through the octopaminergic system and the activation of a cyclic AMP pathway.


Full text loading...


Data & Media loading...

Article metrics loading...



Can't access your account?
  • Key

  • Full access
  • Open Access
  • Partial/No accessInformation