Cookies Policy
X

This site uses cookies. By continuing to browse the site you are agreeing to our use of cookies.

I accept this policy

Find out more here

Levels of catecholamines and 5-hydroxytryptamine and eating behavior in lateral hypothalamic aphagic rats

No metrics data to plot.
The attempt to load metrics for this article has failed.
The attempt to plot a graph for these metrics has failed.
The full text of this article is not currently available.

Brill’s MyBook program is exclusively available on BrillOnline Books and Journals. Students and scholars affiliated with an institution that has purchased a Brill E-Book on the BrillOnline platform automatically have access to the MyBook option for the title(s) acquired by the Library. Brill MyBook is a print-on-demand paperback copy which is sold at a favorably uniform low price.

This Article is currently unavailable for purchase.
Add to Favorites
You must be logged in to use this functionality

Cover image Placeholder

Male rats injected with 6-hydroxydopamine in the lateral hypothalamus did not eat food pellets but ingested an intraorally infused nutritive solution. This 'intraoral intake test' activates consummatory ingestive behavior, the responses used to ingest food, but ignores appetitive ingestive behavior. If given three daily intraoral intake tests, 6-hydroxydopamine-treated rats defended a low body weight, and they were oversensitive to the inhibitory effect of cholecystokinin octapeptide. The concentration of dopamine in the dorsal and ventral striatum was decreased by > 75%, 13 days after the 6-hydroxydopamine treatment, whereas the effect in the frontal cortex was less pronounced. The concentration of noradrenaline and 5-hydroxytryptamine was somewhat less affected, while that of glutamate and cholecystokinin octapeptide was markedly less affected by the 6-hydroxydopamine lesion. Feeding behavior and body weight regulatory competence is, thus, in part retained in rats with massive damage to dopamine neural networks. It is suggested that these networks are not required for consummatory but for appetitive ingestive behavior and for proper perception of the sensory and hormonal signals from the gastrointestinal tract.

10.1163/156939103322580544
/content/journals/10.1163/156939103322580544
dcterms_title,pub_keyword,dcterms_description,pub_author
10
5
Loading
Loading

Full text loading...

/content/journals/10.1163/156939103322580544
Loading

Data & Media loading...

http://brill.metastore.ingenta.com/content/journals/10.1163/156939103322580544
Loading

Article metrics loading...

/content/journals/10.1163/156939103322580544
2017-10-21

Sign-in

Can't access your account?
  • Key

  • Full access
  • Open Access
  • Partial/No accessInformation