Cookies Policy

This site uses cookies. By continuing to browse the site you are agreeing to our use of cookies.

I accept this policy

Find out more here

Salivary concentration of 5-hydroxytryptamine in patients with bulimia nervosa

No metrics data to plot.
The attempt to load metrics for this article has failed.
The attempt to plot a graph for these metrics has failed.
The full text of this article is not currently available.

Brill’s MyBook program is exclusively available on BrillOnline Books and Journals. Students and scholars affiliated with an institution that has purchased a Brill E-Book on the BrillOnline platform automatically have access to the MyBook option for the title(s) acquired by the Library. Brill MyBook is a print-on-demand paperback copy which is sold at a favorably uniform low price.

This Article is currently unavailable for purchase.
Add to Favorites
You must be logged in to use this functionality

Patients with bulimia nervosa (BN) have disturbances of mood and behavior related to monoamine activities. There have been no reports concerning salivary concentrations of 5-hydroxytryptamine (5-HT) in patients with eating disorders such as anorexia nervosa (AN) and BN. In order to elucidate the involvement of 5-HT in eating disorders, 5-HT levels in the saliva of patients with BN were measured. Salivary 5-HT levels in patients with avoidant personality disorder (APD) were also measured as an active control. 5-HT levels in the saliva of patients with BN and APD were compared with those of 32 healthy volunteers. Simultaneously, salivary 3,4-dihydroxyphenylacetic acid (DOPAC) was measured using HPLC-ECD. 5-HT levels were 41.04 ± 14.41 in 11 patients with BN (10 women and 1 man, average age 19.6 years), 78.55 ± 45.55 in 5 patients with APD (3 women and 2 men, average age 19.2 years) and 8.91 ± 1.10 ng/ml in 32 healthy controls (25 women and 7 men, average age 21.7 years), respectively. This is the first report that salivary concentrations of 5-HT were significantly higher in BN (p < 0.05) and in APD than those in healthy controls. We found no significant differences among the salivary DOPAC levels in BN, APD and those of healthy controls. There were no significant differences in body mass index among the three groups. 5-HT concentrations in the saliva may be a useful marker of stress or eating disorders.


Full text loading...


Data & Media loading...

Article metrics loading...



Can't access your account?
  • Key

  • Full access
  • Open Access
  • Partial/No accessInformation