Cookies Policy

This site uses cookies. By continuing to browse the site you are agreeing to our use of cookies.

I accept this policy

Find out more here

Major sex differences in the development of myelination are prominent in song system nucleus HVC but not lMAN

No metrics data to plot.
The attempt to load metrics for this article has failed.
The attempt to plot a graph for these metrics has failed.
The full text of this article is not currently available.

Brill’s MyBook program is exclusively available on BrillOnline Books and Journals. Students and scholars affiliated with an institution that has purchased a Brill E-Book on the BrillOnline platform automatically have access to the MyBook option for the title(s) acquired by the Library. Brill MyBook is a print-on-demand paperback copy which is sold at a favorably uniform low price.

Access this article

+ Tax (if applicable)
Add to Favorites
You must be logged in to use this functionality

image of Animal Biology
For more content, see Archives Néerlandaises de Zoologie (Vol 1-17) and Netherlands Journal of Zoology (Vol 18-52).

Myelination of axonal processes is an important feature for setting up the connectivity in the neuronal network. Processes of myelination are also indicatives for changes in neuronal plasticity. The primary objective of this paper was to determine the time course of myelination—expressed in the number of myelinated profiles and the overall coverage of myelinated profiles per unit area of tissue—in two well-known song nuclei (HVC and lMAN) that have been implicated in song recognition in both male and female birds. While large sex differences have been described for many aspects of morphology in HVC, lMAN is much less dimorphic. Therefore, we wanted to know: 1) whether these differences in the extent of sexual dimorphism are also reflected in the extent of myelination; and 2) whether spatial and temporal features of myelin appearance differ in these two song nuclei in males. We analysed toluidine blue-stained Epon-embedded semithin sections with high resolution light microscopy using a computer-based morphometric system. Myelination in HVC increases substantially in males at 60 days of age, whereas, in lMAN, myelination starts early in development with an additional increase between 60 days and adulthood. In contrast to female HVC, where no changes in myelination can be observed throughout development, myelination in female lMAN increases. This increase, however, is of a different dynamic and of lesser extent in comparison to males. Henceforth, myelination in males lasts until adulthood, indicating long lasting plastic changes in both song nuclei, HVC and lMAN, whereas in females myelination is only prominent in lMAN.


Full text loading...


Data & Media loading...

Article metrics loading...



Can't access your account?
  • Tools

  • Add to Favorites
  • Printable version
  • Email this page
  • Subscribe to ToC alert
  • Get permissions
  • Recommend to your library

    You must fill out fields marked with: *

    Librarian details
    Your details
    Why are you recommending this title?
    Select reason:
    Animal Biology — Recommend this title to your library
  • Export citations
  • Key

  • Full access
  • Open Access
  • Partial/No accessInformation