Effect of Grade I and II Intraventricular Hemorrhage on Visuocortical Function in Very Low Birth Weight Infants
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The neurological outcome for infants with Grade I/II intraventricular hemorrhage (IVH) is debated. The aim of this study was to determine whether very low birth weight infants (VLBW, <1500 g) with Grade I/II (IVH) have altered visuocortical activity compared with infants with no IVH. We assessed the quantitative swept parameter visual evoked potential (sVEP) responses evoked by three different visual stimuli. Data from 52 VLBW infants were compared with data from 13 infants with Grade I or II IVH, enrolled at 5–7 months corrected age. Acuity thresholds and suprathreshold response amplitudes were compared. Grating acuity (GA), contrast sensitivity (CS) and vernier acuity (VA) were each worse in the Grade I/II IVH compared with the no IVH groups (8.24 cpd in IVH group vs. 13.07 cpd in no IVH group for GA; 1.44% vs. 1.18% for CS and 1.55 arcmin vs. 0.58 arcmin for VA). The slopes of the response amplitude for CS and VA were significantly lower in IVH infants. The spatial frequency tuning function was shifted downward on the spatial frequency axis, without a change in slope. These results indicate that Grade I/II IVH are associated with deleterious effects on cortical vision development and function.
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Evrard P. , Gressens P. , Volpe J. J. ( 1992). "New concepts to understand the neurological consequences of subcortical lesions in the premature brain", Biol. Neonate Vol 61, 1– 3. http://dx.doi.org/10.1159/000243525
Good W. V. ( 2001). "Development of a quantitative method to measure vision in children with chronic cortical visual impairment", Trans. Amer. Ophthalmol. Soc. Vol 99, 253– 269.
Hack M. , Horbar J. D. , Malloy M. H. , Tyson J. E. , Wright E. , Wright L. ( 1991). "Very low birth weight outcomes of the National Institute of Child Health and Human Development Neonatal Network", Pediatrics Vol 87, 587– 597.
Hack M. , Klein N. K. , Taylor H. G. ( 1995). "Long-term developmental outcomes of low birth weight infants", Future Child Vol 5, 176– 196. http://dx.doi.org/10.2307/1602514
Hille E. T. , den Ouden A. L. , Bauer L. , van den Oudenrijn C. , Brand R. , Verloove-Vanhorick S. P. ( 1994). "School performance at nine years of age in very premature and very low birth weight infants: perinatal risk factors and predictors at five years of age. Collaborative Project on Preterm and Small for Gestational Age (POPS) Infants in The Netherlands", J. Pediat. Vol 125, 426– 434. http://dx.doi.org/10.1016/S0022-3476(05)83290-1
Hunt J. V. , Cooper B. A. , Tooley W. H. ( 1988). "Very low birth weight infants at 8 and 11 years of age: role of neonatal illness and family status", Pediatrics Vol 82, 596– 603.
McCormick M. C. , Brooks-Gunn J. , Workman-Daniels K. , Turner J. , Peckham G. J. ( 1992). "The health and developmental status of very low-birth-weight children at school age", JAMA Vol 267, 2204– 2208. http://dx.doi.org/10.1001/jama.1992.03480160062035
Norcia A. M. ( 1993). "Improving infant evoked response measurement", in: Early Visual Development, Normal and Abnormal, Simons K. (Ed.), pp. 536– 552. Oxford University Press, New York, USA.
O’Connor A. R. , Stephenson T. , Johnson A. , Tobin M. J. , Moseley M. J. , Ratib S. , Ng Y. , Fielder A. R. ( 2002). "Long-term ophthalmic outcome of low birth weight children with and without retinopathy of prematurity", Pediatrics Vol 109, 12– 18. http://dx.doi.org/10.1542/peds.109.1.12
O’Keefe M. , Kafil-Hussain N. , Flitcroft I. , Lanigan B. ( 2001). "Ocular significance of intraventricular haemorrhage in premature infants", Brit. J. Ophthalmol. Vol 85, 357– 359. http://dx.doi.org/10.1136/bjo.85.3.357
Papile L. A. , Burstein J. , Burstein R. , Koffler H. ( 1978). "Incidence and evolution of subependymal and intraventricular hemorrhage: a study of infants with birth weights less than 1,500 gm", J. Pediat. Vol 92, 529– 534. http://dx.doi.org/10.1016/S0022-3476(78)80282-0
Patra K. , Wilson-Costello D. , Taylor H. G. , Mercuri-Minich N. , Hack M. ( 2006). "Grades I–II intraventricular hemorrhage in extremely low birth weight infants: effects on neurodevelopment", J. Pediat. Vol 149, 169– 173. http://dx.doi.org/10.1016/j.jpeds.2006.04.002
Quinn G. E. , Dobson V. , Davitt B. V. , Hardy R. J. , Tung B. , Pedroza C. , Good W. V. ( 2008). "Progression of myopia and high myopia in the early treatment for retinopathy of prematurity study: findings to 3 years of age", Ophthalmology Vol 115, 1058– 1064, e1051. http://dx.doi.org/10.1016/j.ophtha.2007.07.028
Sahni J. , Subhedar N. V. , Clark D. ( 2005). "Treated threshold stage 3 versusspontaneously regressed subthreshold stage 3 retinopathy of prematurity: a study of motility, refractive, and anatomical outcomes at 6 months and 36 months", Brit. J. Ophthalmol. Vol 89, 154– 159. http://dx.doi.org/10.1136/bjo.2004.045815
Skoczenski A. M. , Norcia A. M. ( 1999). "Development of VEP vernier acuity and grating acuity in human infants", Invest. Ophthalmol. Vis. Sci. Vol 40, 2411– 2417.
Sprent P. ( 1989). Applied Non Parametric Statistical Methods. Chapman and Hall, London, UK.
Stevenson D. K. , Wright L. L. , Lemons J. A. , Oh W. , Korones S. B. , Papile L. A. , Bauer C. R. , Stoll B. J. , Tyson J. E. , Shankaran S. , Fanaroff A. A. , Donovan E. F. , Ehrenkranz R. A. , Verter J. ( 1998). "Very low birth weight outcomes of the National Institute of Child Health and Human Development Neonatal Research Network, January 1993 through December 1994", Amer. J. Obstet. Gynecol. Vol 179, 1632– 1639. http://dx.doi.org/10.1016/S0002-9378(98)70037-7
Vohr B. R. , Allan W. C. , Westerveld M. , Schneider K. C. , Katz K. H. , Makuch R. W. , Ment L. R. ( 2003). "School-age outcomes of very low birth weight infants in the indomethacin intraventricular hemorrhage prevention trial", Pediatrics Vol 111, e340– e346. http://dx.doi.org/10.1542/peds.111.4.e340
Whitaker A. , Johnson J. , Sebris S. , Pinto J. , Wasserman G. , Kairam R. , Shaffer D. , Paneth N. ( 1990). "Neonatal cranial ultrasound abnormalities: association with developmental delay at age one in low birth weight infants", J. Dev. Behav. Pediat. Vol 11, 253– 260. http://dx.doi.org/10.1097/00004703-199010000-00006
Whitaker A. H. , Feldman J. F. , Van Rossem R. , Schonfeld I. S. , Pinto-Martin J. A. , Torre C. , Blumenthal S. R. , Paneth N. S. ( 1996). "Neonatal cranial ultrasound abnormalities in low birth weight infants: relation to cognitive outcomes at six years of age", Pediatrics Vol 98, 719– 729.
Woodward L. J. , Edgin J. O. , Thompson D. , Inder T. E. ( 2005). "Object working memory deficits predicted by early brain injury and development in the preterm infant", Brain Vol 128, 2578– 2587. http://dx.doi.org/10.1093/brain/awh618