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Modality Dependent Cross-Modal Functional Reorganization Following Congenital Visual Deprivation within Occipital Areas: A Meta-Analysis of Tactile and Auditory Studies

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For more content, see Seeing and Perceiving and Spatial Vision.

Cross-modal responses in occipital areas appear to be essential for sensory processing in visually deprived subjects. However, it is yet unclear whether this functional recruitment might be dependent on the sensory channel conveying the information. In order to characterize brain areas showing task-independent, but sensory specific, cross-modal responses in blind individuals, we pooled together distinct brain functional studies in a single based meta-analysis according only to the modality conveying experimental stimuli (auditory or tactile).Our approach revealed a specific functional cortical segregation according to the sensory modality conveying the non-visual information, irrespectively from the cognitive features of the tasks. In particular, dorsal and posterior subregions of occipital and superior parietal cortex showed a higher cross-modal recruitment across tactile tasks in blind as compared to sighted individuals. On the other hand, auditory stimuli activated more medial and ventral clusters within early visual areas, the lingual and inferior temporal cortex. These findings suggest a modality-specific functional modification of cross-modal responses within different portions of the occipital cortex of blind individuals. Cross-modal recruitment can thus be specifically influenced by the intrinsic features of sensory information.

Affiliations: 1: 1Laboratory of Clinical Biochemistry and Molecular Biology, University of Pisa, Pisa, Italy

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1. Amedi A. , Merabet L. B. , Bermpohl F. , Pascual-Leone A. ( 2005). "The occipital cortex in the blind lessons about plasticity and vision", Curr. Dir. Psychol. Sci. Vol 14, 306311. http://dx.doi.org/10.1111/j.0963-7214.2005.00387.x
2. Amedi A. , Stern W. M. , Camprodon J. A. , Bermpohl F. , Merabet L. B. , Rotman S. , Hemond C. , Meijer P. , Pascual-Leone A. ( 2007). "Shape conveyed by visual-to-auditory sensory substitution activates the lateral occipital complex", Nat. Neurosci. Vol 10, 687689. http://dx.doi.org/10.1038/nn1912
3. Anurova I. , Renier L. , De Volder A. G. , Carlson S. , Rauschecker J. P. (in press). "Relationship between cortical thickness and functional activation in the early blind", Cereb. Cortex.DOI:
4. Büchel C. , Price C. , Friston K. ( 1998). "A multimodal language region in the ventral visual pathway", Nature Vol 394, 274277. http://dx.doi.org/10.1038/28389
5. Burton H. , Sinclair R. J. , Dixit S. ( 2010). "Working memory for vibrotactile frequencies: comparison of cortical activity in blind and sighted individuals", Hum. Brain Mapp. Vol 31, 16861701.
6. Chabot N. , Charbonneau V. , Laramée M.-E. , Tremblay R. , Boire D. , Bronchti G. ( 2008). "Subcortical auditory input to the primary visual cortex in anophthalmic mice", Neurosci. Lett. Vol 433, 129134. http://dx.doi.org/10.1016/j.neulet.2008.01.003
7. Cohen L. G. , Celnik P. , Pascual-Leone A. , Corwell A. , Falz L. , Dambrosia J. , Honda M. , Sadato N. , Gerloff C. , Català M. D. , Hallett M. ( 1997). "Functional relevance of cross-modal plasticity in blind humans", Nature Vol 389, 180183. http://dx.doi.org/10.1038/38278
8. Collignon O. , Davare M. , Olivier E. , De Volder A. G. ( 2009). "Reorganisation of the right occipito-parietal stream for auditory spatial processing in early blind humans. A transcranial magnetic stimulation study", Brain Topogr. Vol 21, 232240. http://dx.doi.org/10.1007/s10548-009-0075-8
9. Collignon O. , Dormal G. , Albouy G. , Vandewalle G. , Voss P. , Phillips C. , Lepore F. ( 2013). "Impact of blindness onset on the functional organization and the connectivity of the occipital cortex", Brain Vol 136, 27692783. http://dx.doi.org/10.1093/brain/awt176
10. Collignon O. , Vandewalle G. , Voss P. , Albouy G. , Charbonneau G. , Lassonde M. , Lepore F. ( 2011). "Functional specialization for auditory–spatial processing in the occipital cortex of congenitally blind humans", Proc. Natl Acad. Sci. USA Vol 108, 44354440. http://dx.doi.org/10.1073/pnas.1013928108
11. De Volder A. G. , Toyama H. , Kimura Y. , Kiyosawa M. , Nakano H. , Vanlierde A. , Wanet- Defalque M.-C. , Mishina M. , Oda K. , Iishiwata K. ( 2001). "Auditory triggered mental imagery of shape involves visual association areas in early blind humans", NeuroImage Vol 14, 129139. http://dx.doi.org/10.1006/nimg.2001.0782
12. Desgent S. , Ptito M. ( 2012). "Cortical GABAergic interneurons in cross-modal plasticity following early blindness", Neural Plast. Vol 2012, 590725.
13. Eickhoff S. B. , Amunts K. , Mohlberg H. , Zilles K. ( 2006). "The human parietal operculum. II. Stereotaxic maps and correlation with functional imaging results", Cereb. Cortex Vol 16, 268279. http://dx.doi.org/10.1093/cercor/bhi106
14. Eickhoff S. B. , Bzdok D. , Laird A. R. , Kurth F. , Fox P. T. ( 2012). "Activation likelihood estimation meta-analysis revisited", NeuroImage Vol 59, 23492361. http://dx.doi.org/10.1016/j.neuroimage.2011.09.017
15. Eickhoff S. B. , Laird A. R. , Grefkes C. , Wang L. E. , Zilles K. , Fox P. T. ( 2009). "Coordinate-based activation likelihood estimation meta-analysis of neuroimaging data: a random-effects approach based on empirical estimates of spatial uncertainty", Hum. Brain Mapp. Vol 30, 29072926. http://dx.doi.org/10.1002/hbm.20718
16. Farrell M. J. , Laird A. R. , Egan G. F. ( 2005). "Brain activity associated with painfully hot stimuli applied to the upper limb: a meta-analysis", Hum. Brain Mapp. Vol 25, 129139. http://dx.doi.org/10.1002/hbm.20125
17. Fiehler K. , Reuschel J. , Rösler F. ( 2009). "Early non-visual experience influences proprioceptive-spatial discrimination acuity in adulthood", Neuropsychologia Vol 47, 897906. http://dx.doi.org/10.1016/j.neuropsychologia.2008.12.023
18. Fishman M. C. , Michael P. ( 1973). "Integration of auditory information in the cat’s visual cortex", Vision Res. Vol 8, 14151419. http://dx.doi.org/10.1016/0042-6989(73)90002-3
19. Frasnelli J. , Collignon O. , Voss P. , Lepore F. ( 2011). "Crossmodal plasticity in sensory loss", Prog. Brain Res. Vol 191, 233249.
20. Gougoux F. , Belin P. , Voss P. , Lepore F. , Lassonde M. , Zatorre R. J. ( 2009). "Voice perception in blind persons: a functional magnetic resonance imaging study", Neuropsychologia Vol 47, 29672974. http://dx.doi.org/10.1016/j.neuropsychologia.2009.06.027
21. Gougoux F. , Zatorre R. J. , Lassonde M. , Voss P. , Lepore F. ( 2005). "A functional neuroimaging study of sound localization: visual cortex activity predicts performance in early-blind individuals", PLoS Biol. Vol 3, e27. http://dx.doi.org/10.1371/journal.pbio.0030027
22. Inui K. , Okamoto H. , Miki K. , Gunji A. , Kakiji R. ( 2006). "Serial and parallel processing in the human auditory cortex: a magnetoencephalographic study", Cereb. Cortex Vol 16, 1830. http://dx.doi.org/10.1093/cercor/bhi080
23. Ioannides A. A. , Liu L. , Poghosyan Y. , Saridis G. A. , Gjedde A. , Ptito M. , Kupers R. ( 2013). "MEG reveals a fast pathway from somatosensory cortex to occipital areas via posterior parietal cortex in a blind subject", Front. Hum. Neurosci. Vol 7, 429. http://dx.doi.org/10.3389/fnhum.2013.00429
24. Kalberlah C. , Villringer A. , Pleger B. ( 2013). "Dynamic causal modeling suggests serial processing of tactile vibratory stimuli in the human somatosensory cortex — an fMRI study", NeuroImage Vol 74, 164171. http://dx.doi.org/10.1016/j.neuroimage.2013.02.018
25. Kitada R. , Okamoto Y. , Sasaki A. T. , Kochiyama T. , Miyahara M. , Lederman S. J. , Sadato N. ( 2013). "Early visual experience and the recognition of basic facial expressions: involvement of the middle temporal and inferior frontal gyri during haptic identification by the early blind", Front. Hum. Neurosci. Vol 7, 7. http://dx.doi.org/10.3389/fnhum.2013.00007
26. Klemen J. , Chambers C. D. ( 2012). "Current perspectives and methods in studying neural mechanisms of multisensory interactions", Neurosci. Biobehav. Rev. Vol 36, 111133. http://dx.doi.org/10.1016/j.neubiorev.2011.04.015
27. Klinge C. , Eippert F. , Röder B. , Büchel C. ( 2010). "Corticocortical connections mediate primary visual cortex responses to auditory stimulation in the blind", J. Neurosci. Vol 30, 1279812805. http://dx.doi.org/10.1523/JNEUROSCI.2384-10.2010
28. Kupers R. , Fumal A. , De Noordhout A. M. , Gjedde A. , Schoenen J. , Ptito M. ( 2006). "Transcranial magnetic stimulation of the visual cortex induces somatotopically organized qualia in blind subjects", Proc. Natl Acad. Sci. USA Vol 103, 1325613260. http://dx.doi.org/10.1073/pnas.0602925103
29. Kupers R. , Pietrini P. , Ricciardi E. , Ptito M. ( 2011). "The nature of consciousness in the visually deprived brain", Front. Psychol. Vol 2, 19. http://dx.doi.org/10.3389/fpsyg.2011.00019
30. Kupers R. , Ptito M. ( 2011). "Insights from darkness: what the study of blindness has taught us about brain structure and function", Prog. Brain Res. Vol 192, 1731.
31. Kupers R. , Ptito M. ( 2013). "Compensatory plasticity and cross-modal reorganization following early visual deprivation", Neurosci. Biobehav. Rev. Vol 41, 3652. http://dx.doi.org/10.1016/j.neubiorev.2013.08.001
32. Leo A. , Bernardi G. , Handjaras G. , Bonino D. , Ricciardi E. , Pietrini P. ( 2012). "Increased BOLD variability in the parietal cortex and enhanced parieto-occipital connectivity during tactile perception in congenitally blind individuals", Neural Plast. Vol 2012, 720278.
33. Lewis L. B. , Saenz M. , Fine I. ( 2010). "Mechanisms of cross-modal plasticity in early-blind subjects", J. Neurophysiol. Vol 104, 29953008. http://dx.doi.org/10.1152/jn.00983.2009
34. Merabet L. B. , Pascual-Leone A. ( 2010). "Neural reorganization following sensory loss: the opportunity of change", Nat. Rev. Neurosci. Vol 11, 4452. http://dx.doi.org/10.1038/nrn2758
35. Morrell F. ( 1972). "Visual system’s view of acoustic space", Nature Vol 238, 4446. http://dx.doi.org/10.1038/238044a0
36. Noppeney U. ( 2007). "The effects of visual deprivation on functional and structural organization of the human brain", Neurosci. Biobehav. Rev. Vol 31, 11691180. http://dx.doi.org/10.1016/j.neubiorev.2007.04.012
37. Noppeney U. , Friston K. J. , Price C. J. ( 2003). "Effects of visual deprivation on the organization of the semantic system", Brain Vol 126, 16201627. http://dx.doi.org/10.1093/brain/awg152
38. Pascual-Leone A. , Amedi A. , Fregni F. , Merabet L. B. ( 2005). "The plastic human brain cortex", Annu. Rev. Neurosci. Vol 28, 377401. http://dx.doi.org/10.1146/annurev.neuro.27.070203.144216
39. Pascual-Leone A. , Hamilton R. ( 2001). "The metamodal organization of the brain", Prog. Brain Res. Vol 134, 427445.
40. Pascual-Leone A. , Walsh V. , Rothwell J. ( 2000). "Transcranial magnetic stimulation in cognitive neuroscience — virtual lesion, chronometry, and functional connectivity", Curr. Opin. Neurobiol. Vol 10, 232237. http://dx.doi.org/10.1016/S0959-4388(00)00081-7
41. Pietrini P. , Furey M. L. , Ricciardi E. , Gobbini M. I. , Wu W.-H. C. , Cohen L. , Guazzelli M. , Haxby J. V. ( 2004). "Beyond sensory images: object-based representation in the human ventral pathway", Proc. Natl Acad. Sci. USA Vol 101, 56585663. http://dx.doi.org/10.1073/pnas.0400707101
42. Poirier C. , Collignon O. , Scheiber C. , Renier L. , Vanlierde A. , Tranduy D. , Veraart C. , De Volder A. G. ( 2006). "Auditory motion perception activates visual motion areas in early blind subjects", NeuroImage Vol 31, 279285. http://dx.doi.org/10.1016/j.neuroimage.2005.11.036
43. Price C. J. , Devlin J. T. , Moore C. J. , Morton C. , Laird A. R. ( 2005). "Meta-analyses of object naming: effect of baseline", Hum. Brain Mapp. Vol 25, 7082. http://dx.doi.org/10.1002/hbm.20132
44. Ptito M. , Fumal A. , de Noordhout A. M. , Schoenen J. , Gjedde A. , Kupers R. ( 2008). "TMS of the occipital cortex induces tactile sensations in the fingers of blind Braille readers", Exp. Brain Res. Vol 184, 193200. http://dx.doi.org/10.1007/s00221-007-1091-0
45. Ptito M. , Matteau I. , Zhi Wang A. , Paulson O. B. , Siebner H. R. , Kupers R. ( 2012). "Crossmodal recruitment of the ventral visual stream in congenital blindness", Neural Plast. Vol 2012, 304045.
46. Ptito M. , Moesgaard S. M. , Gjedde A. , Kupers R. ( 2005). "Cross-modal plasticity revealed by electrotactile stimulation of the tongue in the congenitally blind", Brain Vol 128, 606614. http://dx.doi.org/10.1093/brain/awh380
47. Raz N. , Amedi A. , Zohary E. ( 2005). "V1 activation in congenitally blind humans is associated with episodic retrieval", Cereb. Cortex Vol 15, 14591468. http://dx.doi.org/10.1093/cercor/bhi026
48. Renier L. A. , Anurova I. , De Volder A. G. , Carlson S. , Vanmeter J. , Rauschecker J. P. ( 2010). "Preserved functional specialization for spatial processing in the middle occipital gyrus of the early blind", Neuron Vol 68, 138148. http://dx.doi.org/10.1016/j.neuron.2010.09.021
49. Ricciardi E. , Bonino D. , Pellegrini S. , Pietrini P. ( 2013). "Mind the blind brain to understand the sighted one! Is there a supramodal cortical functional architecture?" Neurosci. Biobehav. Rev. Vol 41, 6477. http://dx.doi.org/10.1016/j.neubiorev.2013.10.006
50. Ricciardi E. , Pietrini P. ( 2011). "New light from the dark: what blindness can teach us about brain function", Curr. Opin. Neurol. Vol 24, 357363. http://dx.doi.org/10.1097/WCO.0b013e328348bdbf
51. Ricciardi E. , Vanello N. , Sani L. , Gentili C. , Scilingo E. P. , Landini L. , Guazzelli M. , Bicchi A. , Haxby J. V. , Pietrini P. ( 2007). "The effect of visual experience on the development of functional architecture in hMT+", Cereb. Cortex Vol 17, 29332939. http://dx.doi.org/10.1093/cercor/bhm018
52. Sadato N. , Pascual-Leone A. , Grafman J. , Deiber M.-P. , Ibanez V. , Hallett M. ( 1998). "Neural networks for Braille reading by the blind", Brain Vol 121, 12131229. http://dx.doi.org/10.1093/brain/121.7.1213
53. Sadato N. , Pascual-Leone A. , Grafman J. , Ibanez V. , Deiber M.-P. , Dold G. , Hallett M. ( 1996). "Activation of the primary visual cortex by Braille reading in blind subjects", Nature Vol 380, 526528. http://dx.doi.org/10.1038/380526a0
54. Sani L. , Ricciardi E. , Gentili C. , Vanello N. , Haxby J. V. , Pietrini P. ( 2010). "Effects of visual experience on the human MT+ functional connectivity networks: an fMRI study of motion perception in sighted and congenitally blind individuals", Front. Syst. Neurosci. Vol 4, 159. http://dx.doi.org/10.3389/fnsys.2010.00159
55. Turkeltaub P. E. , Eickhoff S. B. , Laird A. R. , Fox M. , Wiener M. , Fox P. ( 2012). "Minimizing within-experiment and within-group effects in activation likelihood estimation meta-analyses", Hum. Brain Mapp. Vol 33, 113. http://dx.doi.org/10.1002/hbm.21186
56. Vanlierde A. , De Volder A. G. , Wanet-Defalque M. C. , Veraart C. ( 2003). "Occipito-parietal cortex activation during visuo-spatial imagery in early blind humans", NeuroImage Vol 19, 698709. http://dx.doi.org/10.1016/S1053-8119(03)00153-8
57. Wager T. D. , Jonides J. , Reading S. ( 2004). "Neuroimaging studies of shifting attention: a meta-analysis", NeuroImage Vol 22, 16791693. http://dx.doi.org/10.1016/j.neuroimage.2004.03.052
58. Wager T. D. , Smith E. E. ( 2003). "Neuroimaging studies of working memory", Cogn. Affect. Behav. Neurosci. Vol 3, 255274. http://dx.doi.org/10.3758/CABN.3.4.255
59. Watkins K. E. , Shakespeare T. J. , O’Donoghue M. C. , Alexander I. , Ragge N. , Cowey A. , Bridge H. ( 2013). "Early auditory processing in area V5/MT+ of the congenitally blind brain", J. Neurosci. Vol 33, 1824218246. http://dx.doi.org/10.1523/JNEUROSCI.2546-13.2013
60. Weeks R. , Horwitz B. , Aziz-Sultan A. , Tian B. , Wessinger C. M. , Cohen L. G. , Hallett M. , Rauschecker J. P. ( 2000). "A positron emission tomographic study of auditory localization in the congenitally blind", J. Neurosci. Vol 20, 26642672.
61. Wolbers T. , Zahorik P. , Giudice N. A. ( 2011). "Decoding the direction of auditory motion in blind humans", NeuroImage Vol 56, 681687. http://dx.doi.org/10.1016/j.neuroimage.2010.04.266
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2014-09-30
2017-09-22

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